Diafert™ is a non-invasive adjunctive In Vitro Fertilization (IVF) selection assay to improve embryo selection during assisted reproductive procedures.
Fertility affects approximately 12% to 15% of all couple of reproductive age. IVF is consistently gaining interest, amongst others due to significant progresses that attract women encountering difficulties to become pregnant and the wish of women to become pregnant which tends to appear later in their life, at a time when fertility has decreased. However, IVF treatments have a number of hurdles for many patients, which include (1) lengthy and demanding procedure: the process involves, amongst others (i) stimulating multiple follicles and eggs to develop (ii) egg retrieval to get the eggs (iii) fertilizing the eggs in the laboratory (iv) embryo transfer to the uterus. Throughout the procedure, the couple is confronted with a high level of stress; (2) low success rates: it is estimated that only 20-25% of the embryos transferred during IVF procedure lead to a birth (Patrizio and Sakkas, 2009). These rates can vary depending of the women’s age, number of embryos transferred, day of embryo transfer and other factors related to IVF centers’ practices; (3) more than half of the births result from multiple pregnancies: the health risks are greatly increased for both the mother and foetus. The risk of early and late miscarriage is also higher; (4) high costs and limitation on reimbursement: economic status and economic factors, the nature of the local healthcare system, public funding and regulation all have an impact on the cost of the IVF treatment for the patient.